Article
Comparative impact of diverse regulatory loci on Staphylococcus aureus biofilm formation.
MicrobiologyOpen - 1 Jun 2015
Atwood Danielle N, Loughran Allister J, Courtney Ashleah P, Anthony Allison C, Meeker Daniel G, Spencer Horace J, Gupta Ravi Kr, Lee Chia Y, Beenken Karen E, Smeltzer Mark S
Abstract excerpt
The relative impact of 23 mutations on biofilm formation was evaluated in the USA300, methicillin-resistant strain LAC. Mutation of sarA, atl, codY, rsbU, and sigB limited biofilm formation in comparison to the parent strain, but the limitation imposed by mutation of sarA was greater than that imposed by mutation of any of these other genes. The reduced biofilm formation of all mutants other than the atl mutant...
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