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Article

Factors contributing to the biofilm-deficient phenotype of Staphylococcus aureus sarA mutants.

PloS one - 1 Jan 2008

Tsang Laura H, Cassat James E, Shaw Lindsey N, Beenken Karen E, Smeltzer Mark S

Abstract excerpt

Mutation of sarA in Staphylococcus aureus results in a reduced capacity to form a biofilm, but the mechanistic basis for this remains unknown. Previous transcriptional profiling experiments identified a number of genes that are differentially expressed both in a biofilm and in a sarA mutant. This included genes involved in acid tolerance and the production of nucleolytic and proteolytic exoenzymes. Based on this...

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PMID: 18846215
DOI: 10.1371/journal.pone.0003361
PMCID: PMC2556392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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