Article
Identification of genes involved in polysaccharide-independent Staphylococcus aureus biofilm formation.
PloS one - 14 Apr 2010
Boles Blaise R, Thoendel Matthew, Roth Aleeza J, Horswill Alexander R
Abstract excerpt
Staphylococcus aureus is a potent biofilm former on host tissue and medical implants, and biofilm growth is a critical virulence determinant for chronic infections. Recent studies suggest that many clinical isolates form polysaccharide-independent biofilms. However, a systematic screen for defective mutants has not been performed to identify factors important for biofilm formation in these strains. We created a...
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