Article
Apolipoprotein L1 gene variants in deceased organ donors are associated with renal allograft failure.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Jun 2015
Freedman B I, Julian B A, Pastan S O, Israni A K, Schladt D, Gautreaux M D, Hauptfeld V, Bray R A, Gebel H M, Kirk A D, Gaston R S, Rogers J, Farney A C, Orlando G, Stratta R J, Mohan S, Ma L, Langefeld C D, Hicks P J, Palmer N D, Adams P L, Palanisamy A, Reeves-Daniel A M, Divers J
Abstract excerpt
Apolipoprotein L1 gene (APOL1) nephropathy variants in African American deceased kidney donors were associated with shorter renal allograft survival in a prior single-center report. APOL1 G1 and G2 variants were genotyped in newly accrued DNA samples from African American deceased donors of kidneys recovered and/or transplanted in Alabama and North Carolina. APOL1 genotypes and allograft outcomes in subsequent...
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