Article
The APOL1 genotype of African American kidney transplant recipients does not impact 5-year allograft survival.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Jul 2012
Lee B T, Kumar V, Williams T A, Abdi R, Bernhardy A, Dyer C, Conte S, Genovese G, Ross M D, Friedman D J, Gaston R, Milford E, Pollak M R, Chandraker A
Abstract excerpt
Apolipoprotein L-1 (APOL1) gene variants are associated with end-stage renal disease in African Americans (AAs). Here we investigate the impact of recipient APOL1 gene distributions on kidney allograft outcomes. We conducted a retrospective analysis of 119 AA kidney transplant recipients, and found that 58 (48.7%) carried two APOL1 kidney disease risk variants. Contrary to the association seen in native kidney...
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