Article
Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation.
Kidney international - 1 Sept 2015
Ma Jun, Divers Jasmin, Palmer Nicholette D, Julian Bruce A, Israni Ajay K, Schladt David, Pastan Stephen O, Chattrabhuti Kryt, Gautreaux Michael D, Hauptfeld Vera, Bray Robert A, Kirk Allan D, Brown W Mark, Gaston Robert S, Rogers Jeffrey, Farney Alan C, Orlando Giuseppe, Stratta Robert J, Guan Meijian, Palanisamy Amudha, Reeves-Daniel Amber M, Bowden Donald W, Langefeld Carl D, Hicks Pamela J, Ma Lijun, Freedman Barry I
Abstract excerpt
Variants in donor multidrug resistance protein 1 (ABCB1) and caveolin 1 (CAV1) genes are associated with renal allograft failure after transplantation in Europeans. Here we assessed transplantation outcomes of kidneys from 368 African American (AA) and 314 European American (EA) deceased donors based on 38 single-nucleotide polymorphisms (SNPs) spanning ABCB1 and 16 SNPs spanning CAV1, including previously...
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