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Article

Patient-derived olfactory mucosa for study of the non-neuronal contribution to amyotrophic lateral sclerosis pathology.

Journal of cellular and molecular medicine - 1 Jun 2015

García-Escudero Vega, Rosales María, Muñoz José Luis, Scola Esteban, Medina Javier, Khalique Hena, Garaulet Guillermo, Rodriguez Antonio, Lim Filip

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a degenerative motor neuron disease which currently has no cure. Research using rodent ALS models transgenic for mutant superoxide dismutase 1 (SOD1) has implicated that glial-neuronal interactions play a major role in the destruction of motor neurons, but the generality of this mechanism is not clear as SOD1 mutations only account for less than 2% of all ALS cases....

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Source

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Identifiers

PMID: 25807871
DOI: 10.1111/jcmm.12488
PMCID: PMC4459844

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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