Article
Exosome derived from murine adipose-derived stromal cells: Neuroprotective effect on in vitro model of amyotrophic lateral sclerosis.
Experimental cell research - 1 Jan 2016
Bonafede Roberta, Scambi Ilaria, Peroni Daniele, Potrich Valentina, Boschi Federico, Benati Donatella, Bonetti Bruno, Mariotti Raffaella
Abstract excerpt
Therapeutic strategies for the fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS) have not yet provided satisfactory results. Interest in stem cells for the treatment of neurodegenerative diseases is increasing and their beneficial action seems to be due to a paracrine effect via the release of exosomes, main mediators of cell-cell communication. Here we wished to assess, in vitro, the efficacy...
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