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The importance of rs1021737 and rs482843 polymorphisms of cystathionine gamma-lyase in the etiology of preeclampsia in the Caucasian population.

Ginekologia polska - 1 Feb 2015

Mrozikiewicz Przemysław M, Bogacz Anna, Omielańczyk Magdalena, Wolski Hubert, Bartkowiak-Wieczorek Joanna, Grześkowiak Edmund, Czerny Bogusław, Drews Krzysztof, Seremak-Mrozikiewicz Agnieszka

Abstract excerpt

INTRODUCTION: Recently an increasing number of reports indicate the participation of genetic factors in the pathogenesis of preeclampsia (PE). The genes involved in the synthesis of nitric oxide that participates in the vasolidation, may play an important role in the development of this disorder. Hydrogen sulfide (H2S) which is produced by cystathionine gamma-lyase exhibits a similar effect to nitric oxide. It is...

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PMID: 25807836
DOI: 10.17772/gp/1998

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