Article
Relationship between cystathionine gamma-lyase gene polymorphism and essential hypertension in Northern Chinese Han population.
Chinese medical journal - 20 Apr 2008
Li Yun, Zhao Qi, Liu Xiao-Li, Wang Lai-Yuan, Lu Xiang-Feng, Li Hong-Fang, Chen Shu-Feng, Huang Jian-Feng, Gu Dong-Feng
Abstract excerpt
BACKGROUND: Hydrogen sulfide (H(2)S) plays an important role in the smooth muscle cell relaxation and thereby participates in the development of hypertension. Cystathionine gamma-lyase is the key enzyme in the endogenous production of H(2)S. Up to now, the reports on the relationship between the polymorphisms of cystathionine gamma-lyase gene (CTH) and essential hypertension (EH) are limited. This study was...
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