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Article

Splice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells.

PloS one - 1 Jan 2015

Sala Cesare, Mattiuz Giorgio, Pietrobono Silvia, Chicca Andrea, Conticello Silvestro G

Abstract excerpt

Activation Induced Deaminase (AID) triggers the antigen-driven antibody diversification processes through its ability to edit DNA. AID dependent DNA damage is also the cause of genetic alterations often found in mature B cell tumors. A number of splice variants of AID have been identified, for which a role in the modulation of its activity has been hypothesized. We have thus tested two of these splice variants,...

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Share to AICDA (Activation-Induced Cytidine Deaminase)
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Immunoglobulin Class Switching

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Source

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Identifiers

PMID: 25803053
DOI: 10.1371/journal.pone.0121719
PMCID: PMC4372541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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