Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell analysis of Sézary syndrome reveals novel markers and shifting gene profiles associated with treatment

7 Apr 2022

Abstract excerpt

Cutaneous T-cell lymphomas (CTCLs) are a spectrum of diseases with varied clinical courses caused by malignant clonal proliferation of skin-tropic T cells. Most patients have an indolent disease course managed with skin-directed therapies. In contrast, others, especially in advanced stages of disease or with specific forms, have aggressive progression and poor median survival. Sézary syndrome (SS), a leukemic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Cutaneous lymphoproliferative disorders research
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35390145
DOI: 10.1182/bloodadvances.2021005991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell analysis of Sézary syndrome reveals novel markers and shifting gene profiles associated with treatmentPMID 35390145Read ↗

Single-Cell Profiling Reveals Targetable Malignant T-Cell Subtypes and Immune Evasion Pathways in Sézary SyndromeSemantic proximity Read ↗

Phenotypic plasticity of malignant T cells in blood and skin of a Sézary syndrome patient revealed by single cell transcriptomicsSemantic proximity Read ↗

Improved Sézary cell detection and novel insights into immunophenotypic and molecular heterogeneity in Sézary syndromeSemantic proximity Read ↗

Transcriptome sequencing in Sézary syndrome identifies Sézary cell and mycosis fungoides-associated lncRNAs and novel transcriptsSemantic proximity Read ↗

Sézary syndrome originates from heavily mutated hematopoietic progenitorsSemantic proximity Read ↗

Single-cell heterogeneity in Sézary syndromeSemantic proximity Read ↗

Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes.Semantic proximity Read ↗

Sézary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3Semantic proximity Read ↗

Sézary syndrome: old enigmas, new targets.Semantic proximity Read ↗

The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.Semantic proximity Read ↗

Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity.Semantic proximity Read ↗

Personalized treatment of Sézary syndrome by targeting a novel <i><scp>CTLA</scp>4</i>:<i><scp>CD</scp>28</i> fusionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.