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Article

Polymorphisms in endothelin system genes, arsenic levels and obesity risk.

PloS one - 1 Jan 2015

Martínez-Barquero Vanesa, de Marco Griselda, Martínez-Hervas Sergio, Rentero Pilar, Galan-Chilet Inmaculada, Blesa Sebastian, Morchon David, Morcillo Sonsoles, Rojo Gemma, Ascaso Juan Francisco, Real José Tomás, Martín-Escudero Juan Carlos, Chaves Felipe Javier

Abstract excerpt

BACKGROUND/OBJECTIVES: Obesity has been linked to morbidity and mortality through increased risk for many chronic diseases. Endothelin (EDN) system has been related to endothelial function but it can be involved in lipid metabolism regulation: Receptor type A (EDNRA) activates lipolysis in adipocytes, the two endothelin receptors mediate arsenic-stimulated adipocyte dysfunction, and endothelin system can regulate...

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Source

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Identifiers

PMID: 25799405
DOI: 10.1371/journal.pone.0118471
PMCID: PMC4370725

Genes

EDNRB
EDNRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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