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Genetic interaction in the association between oxidative stress and diabetes in the Spanish population.

Free radical biology & medicine - 20 Aug 2023

Melero Rebeca, Quiroz-Rodríguez Maria Elena, Lara-Hernández Francisco, Redón Josep, Sáez Guillermo, Briongos-Figuero Laisa S, Abadía-Otero Jessica, Martín-Escudero Juan Carlos, Chaves F Javier, Ayala Guillermo, García-García Ana-Bárbara

Abstract excerpt

Oxidative stress (OS) is a relevant intermediate mechanism involved in Type 2 Diabetes Mellitus (T2D) development. To date, the interaction between OS parameters and variations in genes related to T2D has not been analyzed. AIMS: To study the genetic interaction of genes potentially related to OS levels (redox homeostasis, renin-angiotensin-aldosterone system, endoplasmic stress response, dyslipidemia, obesity...

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PMID: 37268047
DOI: 10.1016/j.freeradbiomed.2023.05.030

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