Functional G894T (rs1799983) polymorphism and intron-4 VNTR variant of nitric oxide synthase (NOS3) gene are susceptibility biomarkers of obesity among Tunisians.

doi:10.1016/j.orcp.2015.04.008

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Article

Functional G894T (rs1799983) polymorphism and intron-4 VNTR variant of nitric oxide synthase (NOS3) gene are susceptibility biomarkers of obesity among Tunisians.

Obesity research & clinical practice - 1 Jan 2000

Nasr Hela Ben, Dimassi Saloua, M'hadhbi Refka, Debbabi Haithem, Kortas Mondher, Tabka Zouhair, Chahed Karim

Abstract excerpt

OBJECTIVE: The endothelial nitric oxide synthase (NOS3) has been shown to play a role in the modulation of lipolysis. The goal of this study was to examine the impact of the G894T (rs1799983) and a 27 bp variable number of tandem repeats (VNTR 4a/b) of NOS3 gene on obesity in a sample of the Tunisian population. RESEARCH METHODS AND PROCEDURES: The study included 211 normal weight subjects and 183 obese patients....

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PMID: 25956856
DOI: 10.1016/j.orcp.2015.04.008

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NOS3

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