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Article

Studies of the association of Arg72Pro of tumor suppressor protein p53 with type 2 diabetes in a combined analysis of 55,521 Europeans.

PloS one - 20 Jan 2011

Burgdorf Kristoffer Sølvsten, Grarup Niels, Justesen Johanne Marie, Harder Marie Neergaard, Witte Daniel Rinse, Jørgensen Torben, Sandbæk Annelli, Lauritzen Torsten, Madsbad Sten, Hansen Torben, Pedersen Oluf

Abstract excerpt

AIMS: A study of 222 candidate genes in type 2 diabetes reported association of variants in RAPGEF1, ENPP1, TP53, NRF1, SLC2A2, SLC2A4 and FOXC2 with type 2 diabetes in 4,805 Finnish individuals. We aimed to replicate these associations in a Danish case-control study and to substantiate any replicated associations in meta-analyses. Furthermore, we evaluated the impact on diabetes-related intermediate traits in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21283750
DOI: 10.1371/journal.pone.0015813
PMCID: PMC3024396

Genes

ENPP1
FOXC2
NRF1
RAPGEF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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