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Association study of IL10 and IL23R-IL12RB2 in Iranian patients with Behçet's disease.

Arthritis and rheumatism - 1 Aug 2012

Xavier Joana M, Shahram Farhad, Davatchi Fereydoun, Rosa Alexandra, Crespo Jorge, Abdollahi Bahar Sadeghi, Nadji Abdolhadi, Jesus Gorete, Barcelos Filipe, Patto José Vaz, Shafiee Niloofar Mojarad, Ghaderibarim Fahmida, Oliveira Sofia A

Abstract excerpt

OBJECTIVE: Independent replication of the findings from genome-wide association studies (GWAS) remains the gold standard for results validation. Our aim was to test the association of Behçet's disease (BD) with the interleukin-10 gene (IL10) and the IL-23 receptor-IL-12 receptor β2 (IL23R-IL12RB2) locus, each of which has been previously identified as a risk factor for BD in 2 different GWAS. METHODS: Six...

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PMID: 22378604
DOI: 10.1002/art.34437

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