Article
On the genetics of the Silk Route: association analysis of HLA, IL10, and IL23R-IL12RB2 regions with Behçet's disease in an Iranian population.
Immunogenetics - 1 Jun 2015
Carapito Raphael, Shahram Farhad, Michel Sandra, Le Gentil Marion, Radosavljevic Mirjana, Meguro Akira, Abdollahi Bahar Sadeghi, Inoko Hidetoshi, Ota Masao, Davatchi Fereydoun, Bahram Seiamak
Abstract excerpt
Despite that the association of Behçet's disease (BD) with the HLA-B5 was first established in the 1970s, a number of recent genome-wide association studies have both confirmed and furthered this association--in various populations--to individual SNPs both inside and outside the HLA. The former include HLA-B, MICA, and HLA-A, while the latter encompass IL10 and IL23R-IL12RB2 regions. The present study examined...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.