Article
SPP1 promoter polymorphisms and glioma risk in a Chinese Han population.
Journal of human genetics - 1 Jul 2010
Chen Juxiang, Wu Qihan, Lu Yicheng, Xu Tao, Huang Yan, Ribas Judit, Ni Xiaohua, Hu Guohan, Huang Fengping, Zhou Liangfu, Lu Daru
Abstract excerpt
SPP1 was found to be significantly upregulated in many kinds of malignant tumors, including gliomas. Considering that gene polymorphisms have been implicated in the development of gliomas, we performed an association study between SPP1 functional promoter region polymorphisms and glioma risk in a Chinese population. We found significant evidence of an association between SPP1 promoter polymorphisms and glioma...
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