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Article

Association between secreted phosphoprotein-1 (SPP1) polymorphisms and low bone mineral density in women.

PloS one - 1 Jan 2014

Chen Jen-Hau, Chen Yen-Ching, Mao Chien-Lin, Chiou Jeng-Min, Tsao Chwen Keng, Tsai Keh-Sung

Abstract excerpt

BACKGROUND: A recent meta-analysis found that secreted phosphoprotein-1 (SPP1) can predict the risk of both osteoporosis and fracture. No study has explored the association of SPP1 haplotype-tagging single nucleotide polymorphisms (htSNPs) and haplotypes with bone mineral density (BMD). METHODS: This is a cross-sectional study. A total of 1,313 healthy Taiwanese women aged 40 to 55 years were recruited from MJ...

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Source

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Identifiers

PMID: 24831687
DOI: 10.1371/journal.pone.0097428
PMCID: PMC4022728

Genes

SPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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