Article
Expression of Hepatitis C Virus Core and E2 antigenic recombinant proteins and their use for development of diagnostic assays.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 May 2015
Ali Amjad, Nisar Muhammad, Idrees Muhammad, Rafique Shazia, Iqbal Muhammad
Abstract excerpt
BACKGROUND: Early diagnosis of HCV infection is based on detection of antibodies against HCV proteins using recombinant viral antigens. The present study was designed to select, clone and express the antigenic regions of Core and E2 genes from local HCV-3a genotype and to utilize the antigenic recombinant proteins (Core & E2) to develop highly sensitive, specific and economical diagnostic assays for detection of...
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