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Article

Dimethylglycine Deficiency and the Development of Diabetes.

Diabetes - 1 Aug 2015

Magnusson Martin, Wang Thomas J, Clish Clary, Engström Gunnar, Nilsson Peter, Gerszten Robert E, Melander Olle

Abstract excerpt

Experimental studies have suggested possible protective effects of dimethylglycine (DMG) on glucose metabolism. DMG is degraded to glycine through a DMG-dehydrogenase (DMGDH)-catalyzed reaction, and this is the only known pathway for the breakdown of DMG in mammals. In this study, we aimed to ide...

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Identifiers

PMID: 25795213
DOI: 10.2337/db14-1863
PMCID: PMC4512219

Genes

DMGDH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25795213-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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