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Article

Genetic analysis of advanced glycation end products in the DHS MIND study.

Gene - 15 Jun 2016

Adams Jeremy N, Raffield Laura M, Martelle Susan E, Freedman Barry I, Langefeld Carl D, Carr J Jeffrey, Cox Amanda J, Bowden Donald W

Abstract excerpt

Advanced glycation end-products (AGEs) are a diverse group of molecules produced by the non-enzymatic addition of glucose to proteins, lipids, and nucleic acids. AGE levels have been associated with hyperglycemia and diabetic complications, especially in animal models, but less clearly in human studies. We measured total serum AGEs using an enzyme linked immunosorbant assay (ELISA) in 506 subjects from 246...

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Identifiers

PMID: 26915486
DOI: 10.1016/j.gene.2016.02.029
PMCID: PMC4827154

Genes

AGER
FBXO33
ISCA2
MACROD2
NPC2
ZBTB38

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