Article
Prediction of the damage-associated non-synonymous single nucleotide polymorphisms in the human MC1R gene.
PloS one - 1 Jan 2015
Hepp Diego, Gonçalves Gislene Lopes, de Freitas Thales Renato Ochotorena
Abstract excerpt
The melanocortin 1 receptor (MC1R) is involved in the control of melanogenesis. Polymorphisms in this gene have been associated with variation in skin and hair color and with elevated risk for the development of melanoma. Here we used 11 computational tools based on different approaches to predict the damage-associated non-synonymous single nucleotide polymorphisms (nsSNPs) in the coding region of the human MC1R...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.