Article
Genetic and phenotypic variation in UGT2B17, a testosterone-metabolizing enzyme, is associated with BMI in males.
Pharmacogenetics and genomics - 1 May 2015
Zhu Andy Z X, Cox Lisa S, Ahluwalia Jasjit S, Renner Caroline C, Hatsukami Dorothy K, Benowitz Neal L, Tyndale Rachel F
Abstract excerpt
OBJECTIVE: A number of candidate gene and genome-wide association studies have identified significant associations between single nucleotide polymorphisms, particularly in FTO and MC4R, and body weight. However, the association between copy number variation and body weight is less understood. Anabolic androgenic steroids, such as testosterone, can regulate body weight. In humans, UDP-glucuronosyltransferase 2B17...
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