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Article

The effect of copy number variation in the phase II detoxification genes UGT2B17 and UGT2B28 on colorectal cancer risk.

Cancer - 1 Jul 2013

Angstadt Andrea Y, Berg Arthur, Zhu Junjia, Miller Paige, Hartman Terryl J, Lesko Samuel M, Muscat Joshua E, Lazarus Philip, Gallagher Carla J

Abstract excerpt

BACKGROUND: Genetic polymorphisms in combination with the Western-style diet, physical inactivity, smoking, excessive alcohol consumption, and obesity have been hypothesized to affect colorectal cancer (CRC) risk. Metabolizers of environmental carcinogenic and endogenous compounds affecting CRC risk include the phase II detoxification UDP-glucuronosyltransferase (UGT) enzymes UGT2B17 and UGT2B28, which are 2 of...

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Identifiers

PMID: 23575887
DOI: 10.1002/cncr.28009
PMCID: PMC3686841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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