Article
The trithorax group and Pc group proteins are differentially involved in heterochromatin formation in Drosophila.
Chromosoma - 1 Feb 2008
Fanti Laura, Perrini Barbara, Piacentini Lucia, Berloco Maria, Marchetti Enzo, Palumbo Gioacchino, Pimpinelli Sergio
Abstract excerpt
In Drosophila, the Polycomb group and trithorax group proteins play a critical role in controlling the expression states of homeotic gene complexes during development. The common view is that these two classes of proteins bind to the homeotic complexes and regulate transcription at the level of chromatin. In the present work, we tested the involvement of both groups in mitotic heterochromatin formation in...
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