Article
The ancestral SgrS RNA discriminates horizontally acquired Salmonella mRNAs through a single G-U wobble pair.
Proceedings of the National Academy of Sciences of the United States of America - 27 Mar 2012
Papenfort Kai, Podkaminski Dimitri, Hinton Jay C D, Vogel Jörg
Abstract excerpt
SgrS RNA is a model for the large class of Hfq-associated small RNAs that act to posttranscriptionally regulate bacterial mRNAs. The function of SgrS is well-characterized in nonpathogenic Escherichia coli, where it was originally shown to counteract glucose-phosphate stress by acting as a repressor of the ptsG mRNA, which encodes the major glucose transporter. We have discovered additional SgrS targets in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
