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Article

Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory.

Cognitive, affective & behavioral neuroscience - 1 Sept 2015

Kim Ana, Fagan Anne M, Goate Alison M, Benzinger Tammie L S, Morris John C, Head Denise

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) has been shown to be important for neuronal survival and synaptic plasticity in the hippocampus in nonhuman animals. The Val66Met polymorphism in the BDNF gene, involving a valine (Val) to methionine (Met) substitution at codon 66, has been associated with lower BDNF secretion in vitro. However, there have been mixed results regarding associations between either...

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Identifiers

PMID: 25784293
DOI: 10.3758/s13415-015-0343-x
PMCID: PMC4529376

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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