Article
Macaques exhibit a naturally-occurring depression similar to humans.
Scientific reports - 18 Mar 2015
Xu Fan, Wu Qingyuan, Xie Liang, Gong Wei, Zhang Jianguo, Zheng Peng, Zhou Qinmin, Ji Yongjia, Wang Tao, Li Xin, Fang Liang, Li Qi, Yang Deyu, Li Juan, Melgiri Narayan D, Shively Carol, Xie Peng
Abstract excerpt
Rodent models have dominated preclinical investigations into the mechanisms of depression. However, these models-which rely on subjecting individual rodents to physical stressors - do not realistically resemble the etiopathological development of depression, which occurs naturally in a social context. A non-human primate model that better reflects the social ethological aspects of depression would be more...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.