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Article

Depression-like behavioral phenotypes by social and social plus visual isolation in the adult female Macaca fascicularis.

PloS one - 1 Jan 2013

Li Xin, Xu Fan, Xie Liang, Ji Yongjia, Cheng Ke, Zhou Qinmin, Wang Tao, Shively Carol, Wu Qingyuan, Gong Wei, Fang Liang, Zhan Qunlin, Melgiri N D, Xie Peng

Abstract excerpt

Major depressive disorder (MDD) is a debilitating psychiatric mood disorder that affects millions of individuals globally. Our understanding of the biological basis of MDD is poor, and current treatments are ineffective in a significant proportion of cases. This current situation may relate to the dominant rodent animal models of depression, which possess translational limitations due to limited homologies with...

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Identifiers

PMID: 24023857
DOI: 10.1371/journal.pone.0073293
PMCID: PMC3762720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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