Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Five winters of pneumococcal serotype replacement in UK carriage following PCV introduction.

Vaccine - 21 Apr 2015

Gladstone Rebecca A, Jefferies Johanna M, Tocheva Anna S, Beard Kate R, Garley David, Chong Wei Wei, Bentley Stephen D, Faust Saul N, Clarke Stuart C

Abstract excerpt

The seven-valent pneumococcal conjugate vaccine (PCV7) was added to the UK national immunisation programme in September 2006. PCV13 replaced PCV7 in April 2010. As carriage precedes disease cases this study collected carried pneumococci from children each winter from 2006/7 to 2010/11 over PCV introduction. Conventional microbiology and whole genome sequencing were utilised to characterise pneumococcal strains....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier State
Share to Nasopharynx

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pneumococcal Infections

Share to Pneumococcal Vaccines

Share to Seasons

Share to Serogroup

Share to Serotyping

Share to Streptococcus pneumoniae

Source

Open in PubMed Open full text

Identifiers

PMID: 25776920
DOI: 10.1016/j.vaccine.2015.03.012
PMCID: PMC4392391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Five winters of pneumococcal serotype replacement in UK carriage following PCV introduction.PMID 25776920Read ↗

Pre-vaccine serotype composition within a lineage signposts its serotype replacement – a carriage study over 7 years following pneumococcal conjugate vaccine use in the UKSemantic proximity Read ↗

Changes in molecular epidemiology of streptococcus pneumoniae causing meningitis following introduction of pneumococcal conjugate vaccination in England and Wales.Semantic proximity Read ↗

Divergent serotype replacement trends and increasing diversity in pneumococcal disease in high income settings reduce the benefit of expanding vaccine valencySemantic proximity Read ↗

Decreased Carriage and Genetic Shifts in the Streptococcus pneumoniae Population After Changing the Seven-valent to the Thirteen-valent Pneumococcal Vaccine in NorwaySemantic proximity Read ↗

Pneumococcal vaccine impacts on the population genomics of non-typeable Haemophilus influenzae.Semantic proximity Read ↗

Temporal analysis of invasive pneumococcal clones from Scotland illustrates fluctuations in diversity of serotype and genotype in the absence of pneumococcal conjugate vaccine.Semantic proximity Read ↗

Impact of a single dose of the 7-valent pneumococcal conjugate vaccine on colonization.Semantic proximity Read ↗

Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic dataSemantic proximity Read ↗

Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing studySemantic proximity Read ↗

Population genomics of pneumococcal carriage in Massachusetts children following introduction of PCV-13.Semantic proximity Read ↗

Stability of the pneumococcal population structure in Massachusetts as PCV13 was introducedSemantic proximity Read ↗

Increase in Serotype 6C Pneumococcal Carriage, United KingdomSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.