Article
Temporal analysis of invasive pneumococcal clones from Scotland illustrates fluctuations in diversity of serotype and genotype in the absence of pneumococcal conjugate vaccine.
Journal of clinical microbiology - 1 Jan 2010
Jefferies J M, Smith A J, Edwards G F S, McMenamin J, Mitchell T J, Clarke S C
Abstract excerpt
In September 2006, the seven-valent pneumococcal conjugate vaccine (PCV7; Prevenar) was introduced into the childhood vaccination schedule in the United Kingdom. We monitored the population of invasive pneumococci in Scotland in the 5 years preceding the introduction of PCV7 by using serogrouping, multilocus sequence typing (MLST), and eBURST analysis. Here, we present a unique analysis of a complete national...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Bacterial Typing Techniques
- Child
- Child, Preschool
- DNA Fingerprinting
- DNA, Bacterial
- Female
- Genotype