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Article

Changes in molecular epidemiology of streptococcus pneumoniae causing meningitis following introduction of pneumococcal conjugate vaccination in England and Wales.

Journal of clinical microbiology - 1 Mar 2013

Pichon Bruno, Ladhani Shamez N, Slack Mary P E, Segonds-Pichon Anne, Andrews Nick J, Waight Pauline A, Miller Elizabeth, George Robert

Abstract excerpt

The introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) in September 2006 has markedly reduced the burden of invasive pneumococcal disease (IPD) including meningitis in England and Wales. This study examined changes in the molecular epidemiology of pneumococcal isolates causing meningitis from July 2004 to June 2009. The Health Protection Agency conducts enhanced pneumococcal surveillance in...

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Identifiers

PMID: 23269742
DOI: 10.1128/JCM.01917-12
PMCID: PMC3592052

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