Article
Correlates between models of virulence for Mycobacterium tuberculosis among isolates of the Central Asian lineage: a case for lysozyme resistance testing?
Infection and immunity - 1 Jun 2015
Pardieu Claire, Casali Nicola, Clark Simon O, Hooper Richard, Williams Ann, Velji Preya, Gonzalo Ximena, Drobniewski Francis
Abstract excerpt
Virulence factors (VFs) contribute to the emergence of new human Mycobacterium tuberculosis strains, are lineage dependent, and are relevant to the development of M. tuberculosis drugs/vaccines. VFs were sought within M. tuberculosis lineage 3, which has the Central Asian (CAS) spoligotype. Three isolates were selected from clusters previously identified as dominant in London, United Kingdom. Strain-associated...
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