Article
Impact of pathobiological diversity of Mycobacterium tuberculosis on clinical features and lethal outcome of tuberculosis.
BMC microbiology - 8 Feb 2022
Mokrousov Igor, Pasechnik Oksana, Vyazovaya Anna, Yarusova Irina, Gerasimova Alena, Blokh Aleksey, Zhuravlev Viacheslav
Abstract excerpt
BACKGROUND: Mycobacterium tuberculosis population in Russia is dominated by the notorious Beijing genotype whose major variants are characterized by contrasting resistance and virulence properties. Here we studied how these strain features could impact the progression of pulmonary tuberculosis (TB) concerning clinical manifestation and lethal outcome. RESULTS: The study sample included 548 M. tuberculosis...
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