Article
[Genetic polymorphism of glutathione-s-transferases theta1 and mu1 in lung cancer].
Voprosy onkologii - 1 Jan 2007
Dmitrieva A I, Sevost'ianova N V, Kolomiets S A, Tkachenko S B, Davydova N A, Cheremisina O V, Novitskiĭ V V
Abstract excerpt
Polymorphism of GSTT1 and GSTM1 variant genes of phase II biotransformation of xenobiotics was studied in 181 patients with lung cancer. Null genotype frequency in cancer patients was higher than in healthy subjects. It was still higher in metastatic cancer disseminated to the regional lymph nodes as compared with localized tumor.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
