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Article

C2cd3 is required for cilia formation and Hedgehog signaling in mouse.

Development (Cambridge, England) - 1 Dec 2008

Hoover Amber N, Wynkoop Aaron, Zeng Huiqing, Jia Jinping, Niswander Lee A, Liu Aimin

Abstract excerpt

Cilia are essential for mammalian embryonic development as well as for the physiological activity of various adult organ systems. Despite the multiple crucial roles that cilia play, the mechanisms underlying ciliogenesis in mammals remain poorly understood. Taking a forward genetic approach, we have identified Hearty (Hty), a recessive lethal mouse mutant with multiple defects, including neural tube defects,...

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Identifiers

PMID: 19004860
DOI: 10.1242/dev.029835
PMCID: PMC3120044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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