Article
NFKB1/NFKBIa polymorphisms are associated with the progression of cervical carcinoma in HPV-infected postmenopausal women from rural area.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2015
Pallavi Singhal, Anoop Kumar, Showket Hussain, Alo Nag, Mausumi Bharadwaj
Abstract excerpt
Human papillomavirus (HPV) is considered as the major etiological agent for development of cervical cancer but alone is not sufficient enough. So, other environmental factors and host genetic background may play an important role in the development of cervical cancer. HPV carries a minimal amount of structural and regulatory proteins so it is apparently dependent on its host for survival. NF-κB/IkB system plays...
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