Article
Cervical Carcinogenesis and Immune Response Gene Polymorphisms: A Review.
Journal of immunology research - 1 Jan 2017
Mehta Akash M, Mooij Merel, Branković Ivan, Ouburg Sander, Morré Servaas A, Jordanova Ekaterina S
Abstract excerpt
The local immune response is considered a key determinant in cervical carcinogenesis after persistent infection with oncogenic, high-risk human papillomavirus (HPV) infections. Genetic variation in various immune response genes has been shown to influence risk of developing cervical cancer, as well as progression and survival among cervical cancer patients. We reviewed the literature on associations of...
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