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Article

NF-κB1 Intronic Region Polymorphisms as Risk Factor for Head and Neck Cancer in HPV-Infected Population from Pakistan.

Current molecular medicine - 1 Jan 2022

Sarwar Sumaira, Tareen Muammad Usman, Sabir Maimoona, Sultan Aneesa, Malik Salman A

Abstract excerpt

BACKGROUND: Head and neck cancer (HNC) develops due to a number of risk factors, including infection of Human Papillomavirus (HPV). The genetic predisposition also plays an important role in deregulating different signaling pathways including the NF-KB pathway. Certain polymorphisms are reported to affect the NF-kB pathway genes. OBJECTIVES: The present research was conducted to study the association of HPV with...

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PMID: 33653249
DOI: 10.2174/1566524021666210302144344

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