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Immediate postoperative minimal residual disease detection with MAESTRO predicts recurrence and survival in head and neck cancer patients treated with surgery

2025-01-28

Abstract excerpt

<h4>Purpose</h4> While circulating tumor DNA (ctDNA) is a promising biomarker for minimal residual disease (MRD) detection in head and neck squamous cell carcinoma (HNSCC), more sensitive assays are needed for accurate MRD detection at clinically-relevant timepoints. Ultrasensitive MRD detection immediately after surgery could guide adjuvant therapy decisions, but early ctDNA dynamics are poorly understood. <h4>Ex...

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Literature Corpus work
e06b3f4a-185f-58ed-9427-178077411612
DOI
10.1101/2025.01.27.25321202
Open publication

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Immediate postoperative minimal residual disease detection with MAESTRO predicts recurrence and survival in head and neck cancer patients treated with surgeryDOI 10.1101/2025.01.27.25321202
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