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Transcriptomic Biomarker Signatures for Discrimination of Oral Cancer Surgical Margins

17 Mar 2022

Abstract excerpt

Relapse after surgery for oral squamous cell carcinoma (OSCC) contributes significantly to morbidity, mortality and poor outcomes. The current histopathological diagnostic techniques are insufficiently sensitive for the detection of oral cancer and minimal residual disease in surgical margins. We used whole-transcriptome gene expression and small noncoding RNA profiles from tumour, close margin and distant margin...

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PMID: 35327656
DOI: 10.3390/biom12030464

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