Article
Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup'ik) population.
Metabolism: clinical and experimental - 1 Jun 2015
Vaughan Laura Kelly, Wiener Howard W, Aslibekyan Stella, Allison David B, Havel Peter J, Stanhope Kimber L, O'Brien Diane M, Hopkins Scarlett E, Lemas Dominick J, Boyer Bert B, Tiwari Hemant K
Abstract excerpt
OBJECTIVE: To identify novel genetic markers of obesity-related traits and to identify gene-diet interactions with n-3 polyunsaturated fatty acid (n-3 PUFA) intake in Yup'ik people. MATERIAL AND METHODS: We measured body composition, plasma adipokines and ghrelin in 982 participants enrolled in the Center for Alaska Native Health Research (CANHR) Study. We conducted a genome-wide SNP linkage scan and targeted...
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