Article
Genetic polymorphisms in carnitine palmitoyltransferase 1A gene are associated with variation in body composition and fasting lipid traits in Yup'ik Eskimos.
Journal of lipid research - 1 Jan 2012
Lemas Dominick J, Wiener Howard W, O'Brien Diane M, Hopkins Scarlett, Stanhope Kimber L, Havel Peter J, Allison David B, Fernandez Jose R, Tiwari Hemant K, Boyer Bert B
Abstract excerpt
Variants of carnitine palmitoyltransferase 1A (CPT1A), a key hepatic lipid oxidation enzyme, may influence how fatty acid oxidation contributes to obesity and metabolic outcomes. CPT1A is regulated by diet, suggesting interactions between gene variants and diet may influence outcomes. The objective of this study was to test the association of CPT1A variants with body composition and lipids, mediated by...
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