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Article

BCL6 - regulated by AhR/ARNT and wild-type MEF2B - drives expression of germinal center markers MYBL1 and LMO2

13 Mar 2015

Abstract excerpt

Genetic heterogeneity is widespread in tumors, but poorly documented in cell lines. According to immunoglobulin hypermutation analysis, the diffuse large B-cell lymphoma cell line U-2932 comprises two subpopulations faithfully representing original tumor subclones. We set out to identify molecular causes underlying subclone-specific expression affecting 221 genes including surface markers and the germinal center...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25769544
DOI: 10.3324/haematol.2014.120048

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