Article
A permutation test for oligoset DNA pooling studies.
PloS one - 1 Jan 2015
Huang Hsiao-Yuan, Lin Jui-Hsiang, Lee Wen-Chung
Abstract excerpt
Case-control association studies often suffer from population stratification bias. A previous triple combination strategy of stratum matching, genomic controlling, and multiple DNA pooling can correct the bias and save genotyping cost. However the method requires researchers to prepare a multitude of DNA pools-more than 30 case-control pooling sets in total (polyset). In this paper, the authors propose a...
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