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Article

The C957T polymorphism in the dopamine receptor D₂ gene modulates domain-general category learning.

Journal of neurophysiology - 1 May 2015

Xie Zilong, Maddox W Todd, McGeary John E, Chandrasekaran Bharath

Abstract excerpt

Adaptive learning from reward and punishment is vital for human survival. Striatal and frontal dopaminergic activities are associated with adaptive learning. For example, the C957T single nucleotide polymorphism of the dopamine receptor D2 (DRD2) gene alters striatal D2 receptor availability and affects individuals' adaptive learning ability. Specifically, individuals with the T/T genotype, which is associated...

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Identifiers

PMID: 25761959
DOI: 10.1152/jn.01005.2014
PMCID: PMC4440239

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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