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Article

The metabolism of lysophosphatidic acids by allelic variants of human soluble epoxide hydrolase.

Drug metabolism and pharmacokinetics - 1 Feb 2015

Purba Endang R, Leuhery Elsa A, Oguro Ami, Imaoka Susumu

Abstract excerpt

Lysophosphatidic acids (LPAs) are phospholipids which have many physiological and pathophysiological functions. The human soluble epoxide hydrolase (sEH) plays a role in the metabolism of xenobiotics through its metabolism of aromatic hydrocarbon epoxides such as styrene oxide. sEH also has a phosphatase activity, and metabolizes LPAs. In this study, we investigated a purified wild-type (WT) and six allelic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25760533
DOI: 10.1016/j.dmpk.2014.09.002

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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