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Article

[Clinical emergence features and implications of hepatitis B virus rtA181T mutation].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Jan 2015

Li Xiaodong, Jiang Lihong, Li Fan, Liu Yan, Dai Jiuzeng, Zhao Pan, Qin Yaqun, Li Jin, Xu Dongping

Abstract excerpt

OBJECTIVE: To determine the mutational profile and clinical implications of the viral reverse-transcriptase (rt)A 181T mutation in hepatitis B virus (HBV) through population-based analysis of clinical samples. METHODS: Serum samples from 3, 013 patients who visited The 302 Hospital (Beijing, China) were investigated.HBV DNA was extracted and HBV mutations and genotypes were determined by direct...

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Identifiers

PMID: 25751382
DOI: 10.3760/cma.j.issn.1007-3418.2015.01.007
PMCID: PMC12769334

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